Interference of hemoglobin D Punjab on measurements of glycated hemoglobin

Hemoglobin sickle D Punjab — a case report

Compound heterozygosity for βS/βD results in a severe hemolytic anemia and a clinical syndrome similar to that of sickle cell disease. Here, we report a case of HbSD Punjab disease. A 10 year old female child residing at Nagpur, Maharashtra presented with severe hemolytic anemia, hepatosplenomegaly and occasional pains in bones and abdomen. Initially, she was thought to be a case of sickle cell...

Interference of hemoglobin D on measurements of hemoglobin A1c by the high-performance liquid chromatography HA-8160 in 27 patients.

Effects of thyroid status on glycated hemoglobin

INTRODUCTION Glycated hemoglobin (HbA1c) can be altered in different conditions. We hypothesize that HbA1c levels may change due to altered thyroid status, possibly due to changes in red blood cell (RBC) turnover. OBJECTIVES The objective of this study was to determine the effects of altered thyroid status on HbA1c levels in individuals without diabetes, with overt hyper- and hypo-thyroidism,...

Biological variability of glycated hemoglobin.

BACKGROUND The measurement of glycated hemoglobin (HbA(1c)) has a pivotal role in monitoring glycemic state in diabetic patients. Furthermore, the American Diabetes Association has recently recommended the use of HbA(1c) for diabetes diagnosis, but a clear definition of the clinically allowable measurement error is still lacking. Information on biological variability of the analyte can be used ...

Hemoglobin constant spring can interfere with glycated hemoglobin measurements by boronate affinity chromatography.

the online Data Supplement). The fetal-specific allele was positively detected in 36 of the 41 SABER analyses in which the fetal genotype was informative (Table 1). When applied as a panel, the assays were able to detect the presence of the paternally inherited, fetal-specific allele in at least one of the informative SNPs in all of the cases (Table 1). There was no false-positive detection. In...